Sulindac is a non-steroid anti-inflammatory drug. NSAIDs are often prescribed to help arthritis patients reduce pain, tenderness, swelling and stiffness of the joints so that they can go about their normal daily activities. This medication works by interfering with the body’s ability to produce an enzyme that causes inflammation.
NSAIDs such as Sulindac increase the risk of sudden heart attack or stroke. Patients who have had previous heart problems or who have had family members who have had heart problems are more likely to have heart attacks or strokes while on Sulindac. Patients who have had bypass surgery should not take this medication.
Using Sulindac also increases the risk of serious stomach problems such as ulcers, bleeding in the stomach and gastrointestinal perforation. For this reason, it’s important to see a doctor right away if you have stomach pain or blood in your stool while on this medication.